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BMCBI
2005
132views more  BMCBI 2005»
14 years 9 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BMCBI
2004
91views more  BMCBI 2004»
14 years 9 months ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl
106
Voted
SIGMOD
2011
ACM
158views Database» more  SIGMOD 2011»
14 years 13 days ago
Workload-aware database monitoring and consolidation
In most enterprises, databases are deployed on dedicated database servers. Often, these servers are underutilized much of the time. For example, in traces from almost 200 producti...
Carlo Curino, Evan P. C. Jones, Samuel Madden, Har...
60
Voted
EUROSYS
2009
ACM
15 years 6 months ago
Transparent checkpoints of closed distributed systems in Emulab
Emulab is a testbed for networked and distributed systems experimentation. Two guiding principles of its design are realism and control of experimentation. There is an inherent te...
Anton Burtsev, Prashanth Radhakrishnan, Mike Hible...