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» Presentations of Structures in Admissible Sets
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BMCBI
2010
189views more  BMCBI 2010»
14 years 10 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2010
131views more  BMCBI 2010»
14 years 10 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
BMCBI
2008
150views more  BMCBI 2008»
14 years 10 months ago
BibGlimpse: The case for a light-weight reprint manager in distributed literature research
Background: While text-mining and distributed annotation systems both aim at capturing knowledge and presenting it in a standardized form, there have been few attempts to investig...
Thomas Tüchler, Golda Velez, Alexandra Graf, ...
BMCBI
2008
149views more  BMCBI 2008»
14 years 10 months ago
Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...
BMCBI
2008
117views more  BMCBI 2008»
14 years 10 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...