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» Primer design using genetic algorithm
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BMCBI
2006
117views more  BMCBI 2006»
13 years 6 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
IMSCCS
2006
IEEE
14 years 9 days ago
Degenerated Primer Design to Amplify the Heavy Chain Variable Region from Immunoglobulin cDNA
Background: The amplification of variable regions of immunoglobulins has become a major challenge in the cloning of antibody genes, whether from hybridoma cell lines or splenic B ...
Wang Ying, Chen Wei, Li Xu, Cheng Bing
BIOCOMP
2006
13 years 7 months ago
Data Mining of ESTs for Genetic Improvement of Salt Tolerance in Wheat
A total of 4,131 expressed sequence tags (ESTs) were selected from wheat EST database (http://wheat.pw.usda.gov/cgi-bin/westsql/est_lib.cgi.) to identify genic regions differing a...
Meral Unal, Ismail Cakmak, Yildiz Aydin, Aysen Yum...
PPSN
2004
Springer
13 years 11 months ago
A Primer on the Evolution of Equivalence Classes of Bayesian-Network Structures
Bayesian networks (BN) constitute a useful tool to model the joint distribution of a set of random variables of interest. To deal with the problem of learning sensible BN models fr...
Jorge Muruzábal, Carlos Cotta
BIOINFORMATICS
2004
59views more  BIOINFORMATICS 2004»
13 years 6 months ago
Efficient selection of unique and popular oligos for large EST databases
EST databases have grown exponentially in recent years and now represent the largest collection of genetic sequences. An important application of these databases is that they conta...
Jie Zheng, Timothy J. Close, Tao Jiang, Stefano Lo...