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BMCBI
2010
227views more  BMCBI 2010»
15 years 1 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2010
156views more  BMCBI 2010»
15 years 1 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2008
98views more  BMCBI 2008»
15 years 1 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2010
135views more  BMCBI 2010»
15 years 1 months ago
Simple and flexible classification of gene expression microarrays via Swirls and Ripples
Background: A simple classification rule with few genes and parameters is desirable when applying a classification rule to new data. One popular simple classification rule, diagon...
Stuart G. Baker
BMCBI
2010
98views more  BMCBI 2010»
15 years 1 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
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