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BMCBI
2005
201views more  BMCBI 2005»
15 years 7 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
ICCAD
2009
IEEE
133views Hardware» more  ICCAD 2009»
15 years 5 months ago
A parallel preconditioning strategy for efficient transistor-level circuit simulation
A parallel computing approach for large-scale SPICE-accurate circuit simulation is described that is based on a new preconditioned iterative solver. The preconditioner involves the...
Heidi Thornquist, Eric R. Keiter, Robert J. Hoekst...
JMLR
2010
179views more  JMLR 2010»
15 years 2 months ago
PAC-Bayesian Analysis of Co-clustering and Beyond
We derive PAC-Bayesian generalization bounds for supervised and unsupervised learning models based on clustering, such as co-clustering, matrix tri-factorization, graphical models...
Yevgeny Seldin, Naftali Tishby
SDM
2011
SIAM
223views Data Mining» more  SDM 2011»
14 years 10 months ago
Characterizing Uncertain Data using Compression
Motivated by sensor networks, mobility data, biology and life sciences, the area of mining uncertain data has recently received a great deal of attention. While various papers hav...
Francesco Bonchi, Matthijs van Leeuwen, Antti Ukko...
RECOMB
2004
Springer
16 years 7 months ago
Learning Regulatory Network Models that Represent Regulator States and Roles
Abstract. We present an approach to inferring probabilistic models of generegulatory networks that is intended to provide a more mechanistic representation of transcriptional regul...
Keith Noto, Mark Craven