Signaling pathways are chains of interacting proteins, through which the cell converts a (usually) extracellular signal into a biological response. The number of known signaling p...
Nattakarn Ratprasartporn, Ali Cakmak, Gultekin &Ou...
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
Hailiang Huang, Lan V. Zhang, Frederick P. Roth, J...
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Although undirected cycles in directed graphs of Bayesian belief networks have been thoroughly studied, little attention has so far been given to a systematic analysis of directed ...
Biological systems consist of many components and interactions between them. In Systems Biology the principal problem is modeling complex biological systems and reconstructing inte...
Marenglen Biba, Stefano Ferilli, Nicola Di Mauro, ...