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BMCBI
2010
148views more  BMCBI 2010»
15 years 4 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2008
175views more  BMCBI 2008»
15 years 4 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2008
133views more  BMCBI 2008»
15 years 4 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
CORR
2010
Springer
92views Education» more  CORR 2010»
15 years 4 months ago
Parameterizing by the Number of Numbers
The usefulness of parameterized algorithmics has often depended on what Niedermeier has called, "the art of problem parameterization." In this paper we introduce and expl...
Michael R. Fellows, Serge Gaspers, Frances A. Rosa...
BMCBI
2006
152views more  BMCBI 2006»
15 years 4 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
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