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» Probabilistic topic modeling for genomic data interpretation
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BMCBI
2005
137views more  BMCBI 2005»
14 years 9 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2008
138views more  BMCBI 2008»
14 years 9 months ago
M-BISON: Microarray-based integration of data sources using networks
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Bernie J. Daigle Jr., Russ B. Altman
BMCBI
2011
14 years 4 months ago
Detection of viral sequence fragments of HIV-1 subfamilies yet unknown
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
Thomas Unterthiner, Anne-Kathrin Schultz, Jan Bull...
ILP
2005
Springer
15 years 2 months ago
Machine Learning for Systems Biology
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Stephen Muggleton
SIGMOD
2006
ACM
156views Database» more  SIGMOD 2006»
15 years 9 months ago
MauveDB: supporting model-based user views in database systems
Real-world data -- especially when generated by distributed measurement infrastructures such as sensor networks -- tends to be incomplete, imprecise, and erroneous, making it impo...
Amol Deshpande, Samuel Madden