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BMCBI
2010
147views more  BMCBI 2010»
14 years 9 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
CIBCB
2005
IEEE
14 years 11 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
SAC
2006
ACM
15 years 3 months ago
Mining and analyzing the topological structure of protein-protein interaction networks
We report a comprehensive evaluation of the topological structure of protein-protein interaction (PPI) networks by mining and analyzing graphs constructed from the publicly availa...
Daniel Duanqing Wu, Xiaohua Hu
BMCBI
2008
134views more  BMCBI 2008»
14 years 9 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
BMCBI
2007
124views more  BMCBI 2007»
14 years 9 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte