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» Problems on RNA Secondary Structure Prediction and Design
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137
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BMCBI
2011
14 years 5 months ago
RAG: An Update to the RNA-As-Graphs Resource
Background: In 2004, we presented a web resource for stimulating the search for novel RNAs, RNA-As-Graphs (RAG), which classified, catalogued, and predicted RNA secondary structur...
Joseph A. Izzo, Namhee Kim, Shereef Elmetwaly, Tam...
ESA
2005
Springer
136views Algorithms» more  ESA 2005»
15 years 7 months ago
Approximating the 2-Interval Pattern Problem
We address the problem of approximating the 2-Interval Pattern problem over its various models and restrictions. This problem, which is motivated by RNA secondary structure predict...
Maxime Crochemore, Danny Hermelin, Gad M. Landau, ...
DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
15 years 8 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...
97
Voted
BMCBI
2007
94views more  BMCBI 2007»
15 years 1 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
15 years 7 months ago
Conserved RNA Pseudoknots
: Pseudoknots are essential for the functioning of many small RNA molecules. In addition, viral RNAs often exhibit pseudoknots that are required at various stages of the viral life...
C. Thurner, Ivo L. Hofacker, Peter F. Stadler