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» Problems on RNA Secondary Structure Prediction and Design
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BMCBI
2008
140views more  BMCBI 2008»
15 years 2 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2007
165views more  BMCBI 2007»
15 years 1 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BIB
2011
14 years 9 months ago
Mutational analysis in RNAs: comparing programs for RNA deleterious mutation prediction
Programs for RNA mutational analysis that are structure-based and rely on secondary structure prediction have been developed and expanded in the past several years. They can be us...
Danny Barash, Alexander Churkin
DNA
2007
Springer
107views Bioinformatics» more  DNA 2007»
15 years 8 months ago
Autonomous Programmable Nanorobotic Devices Using DNAzymes
Abstract. A major challenge in nanoscience is the design of synthetic molecular devices that run autonomously and are programmable. DNA-based synthetic molecular devices have the a...
John H. Reif, Sudheer Sahu
JCB
2000
146views more  JCB 2000»
15 years 1 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag