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» Problems on RNA Secondary Structure Prediction and Design
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BMCBI
2006
72views more  BMCBI 2006»
15 years 2 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
SOFSEM
2010
Springer
15 years 10 months ago
Fast Arc-Annotated Subsequence Matching in Linear Space
An arc-annotated string is a string of characters, called bases, augmented with a set of pairs, called arcs, each connecting two bases. Given arc-annotated strings P and Q the arc-...
Philip Bille, Inge Li Gørtz
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 7 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
ECML
2006
Springer
15 years 5 months ago
Learning Stochastic Tree Edit Distance
Trees provide a suited structural representation to deal with complex tasks such as web information extraction, RNA secondary structure prediction, or conversion of tree structured...
Marc Bernard, Amaury Habrard, Marc Sebban
BMCBI
2008
114views more  BMCBI 2008»
15 years 2 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl