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100
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BMCBI
2008
14 years 10 months ago
2008
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
BMCBI
2010
14 years 10 months ago
2010
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
BMCBI
2008
14 years 10 months ago
2008
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
BMCBI
2007
14 years 10 months ago
2007
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
101
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BMCBI
2008
14 years 10 months ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...