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BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
16 years 2 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
DBPL
1989
Springer
165views Database» more  DBPL 1989»
15 years 11 months ago
Support for Data-Intensive Applications: Conceptual Design and Software Development
In the process of developing an Information System, one passes through stages that include requirements gathering, design specification, and software implementation. The purpose ...
Alexander Borgida, John Mylopoulos, Joachim W. Sch...
IMAMS
2007
245views Mathematics» more  IMAMS 2007»
15 years 8 months ago
Discrete Surface Ricci Flow: Theory and Applications
Conformal geometry is in the core of pure mathematics. Conformal structure is more flexible than Riemaniann metric but more rigid than topology. Conformal geometric methods have p...
Miao Jin, Junho Kim, Xianfeng David Gu
BMCBI
2005
124views more  BMCBI 2005»
15 years 7 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2005
306views more  BMCBI 2005»
15 years 7 months ago
A method for aligning RNA secondary structures and its application to RNA motif detection
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
Jianghui Liu, Jason Tsong-Li Wang, Jun Hu, Bin Tia...