Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
This paper presents a new unified subdivision scheme that is defined over a k-simplicial complex in n-D space with k 3. We first present a series of definitions to facilitate top...