46 search results - page 7 / 10 » Profile-Profile Alignment: A Powerful Tool for Protein Struc... |
BMCBI
2004
14 years 9 months ago
2004
Background: Two of the mostly unsolved but increasingly urgent problems for modern biologists are a) to quickly and easily analyse protein structures and b) to comprehensively min...
100
Voted
BMCBI
2008
14 years 9 months ago
2008
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
NAR
2007
14 years 9 months ago
2007
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
BMCBI
2010
14 years 9 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
92
Voted
BMCBI
2007
14 years 9 months ago
2007
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...