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BMCBI
2007
179views more  BMCBI 2007»
15 years 5 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
153
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BMCBI
2007
140views more  BMCBI 2007»
15 years 5 months ago
Evaluation of high-throughput functional categorization of human disease genes
Background: Biological data that are well-organized by an ontology, such as Gene Ontology, enables high-throughput availability of the semantic web. It can also be used to facilit...
James L. Chen, Yang Liu, Lee T. Sam, Jianrong Li, ...
BMCBI
2007
105views more  BMCBI 2007»
15 years 5 months ago
Finding regulatory elements and regulatory motifs: a general probabilistic framework
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Erik van Nimwegen
172
Voted
BMCBI
2007
207views more  BMCBI 2007»
15 years 5 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...
BMCBI
2007
142views more  BMCBI 2007»
15 years 5 months ago
LinkHub: a Semantic Web system that facilitates cross-database queries and information retrieval in proteomics
nd: A key abstraction in representing proteomics knowledge is the notion of unique identifiers for individual entities (e.g. proteins) and the massive graph of relationships among...
Andrew K. Smith, Kei-Hoi Cheung, Kevin Y. Yip, Mar...
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