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BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
BMCBI
2010
151views more  BMCBI 2010»
14 years 12 months ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon
BMCBI
2007
126views more  BMCBI 2007»
14 years 11 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...
CORR
2007
Springer
167views Education» more  CORR 2007»
14 years 11 months ago
Approximation Algorithms for Orienteering with Time Windows
Orienteering is the following optimization problem: given an edge-weighted graph (directed or undirected), two nodes s, t and a time limit T, find an s-t walk of total length at ...
Chandra Chekuri, Nitish Korula
BMCBI
2005
121views more  BMCBI 2005»
14 years 11 months ago
Evaluation of gene importance in microarray data based upon probability of selection
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
Li M. Fu, Casey S. Fu-Liu