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» Promoter Analysis of Co-regulated Genes in the Yeast Genome
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BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
SDM
2004
SIAM
187views Data Mining» more  SDM 2004»
14 years 11 months ago
Minimum Sum-Squared Residue Co-Clustering of Gene Expression Data
Microarray experiments have been extensively used for simultaneously measuring DNA expression levels of thousands of genes in genome research. A key step in the analysis of gene e...
Hyuk Cho, Inderjit S. Dhillon, Yuqiang Guan, Suvri...
BMCBI
2007
118views more  BMCBI 2007»
14 years 10 months ago
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
Pierre de la Grange, Martin Dutertre, Margot Corre...
BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
RECOMB
2005
Springer
15 years 10 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli