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BMCBI
2007
153views more  BMCBI 2007»
14 years 10 months ago
Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
Background: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel ...
Matthew Landry, Stephen Winters-Hilt
BMCBI
2007
128views more  BMCBI 2007»
14 years 10 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
ISCI
2006
145views more  ISCI 2006»
14 years 10 months ago
Processing count queries over event streams at multiple time granularities
Management and analysis of streaming data has become crucial with its applications in web, sensor data, network traffic data, and stock market. Data streams consist of mostly nume...
Aykut Ünal, Yücel Saygin, Özgü...
JMLR
2008
116views more  JMLR 2008»
14 years 10 months ago
Support Vector Machinery for Infinite Ensemble Learning
Ensemble learning algorithms such as boosting can achieve better performance by averaging over the predictions of some base hypotheses. Nevertheless, most existing algorithms are ...
Hsuan-Tien Lin, Ling Li
JMLR
2008
169views more  JMLR 2008»
14 years 10 months ago
Multi-class Discriminant Kernel Learning via Convex Programming
Regularized kernel discriminant analysis (RKDA) performs linear discriminant analysis in the feature space via the kernel trick. Its performance depends on the selection of kernel...
Jieping Ye, Shuiwang Ji, Jianhui Chen