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» Protein Conformational Flexibility Analysis with Noisy Data
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BMCBI
2011
14 years 4 months ago
ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
Mi-Youn K. Brusniak, Sung-Tat Kwok, Mark Christian...
ISBI
2011
IEEE
14 years 1 months ago
Extraction and analysis of actin networks based on Open Active Contour models
Network structures formed by actin filaments are present in many kinds of fluorescence microscopy images. In order to quantify the conformations and dynamics of such actin fila...
Ting Xu, Hongsheng Li, Tian Shen, Nikola Ojkic, Di...
BMCBI
2010
146views more  BMCBI 2010»
14 years 9 months ago
Booly: a new data integration platform
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
Long H. Do, Francisco F. Esteves, Harvey J. Karten...
CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
COMPLIFE
2006
Springer
15 years 1 months ago
Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...