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» Protein Conformational Flexibility Analysis with Noisy Data
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BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
ARTMED
2005
87views more  ARTMED 2005»
14 years 9 months ago
Fuzzy attributes of a DNA complex: Development of a fuzzy inference engine for codon-"junk" codon delineation
Codons refer to those parts in a DNA complex encoded towards forming a desired set of proteins. Also coexist in the DNA are noncodons (or "junk" codons) whose functions ...
Tomás Arredondo Vidal, Perambur S. Neelakan...
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
14 years 9 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
BMCBI
2008
108views more  BMCBI 2008»
14 years 9 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2006
160views more  BMCBI 2006»
14 years 9 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...