— Analysis of conformational changes is one of the keys to the understanding of protein functions and interactions. For the analysis, we often compare two protein structures, tak...
We have developed a method for the integrative analysis of protein interaction data. It comprises clustering, visualization and data integration components. The method is generall...
Matthias Fellenberg, Kaj Albermann, Alfred Zollner...
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
—We consider the problem of positioning a cloud of points in the Euclidean space Rd , from noisy measurements of a subset of pairwise distances. This task has applications in var...