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» Protein Conformational Flexibility Analysis with Noisy Data
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TCBB
2010
104views more  TCBB 2010»
14 years 8 months ago
Fast Hinge Detection Algorithms for Flexible Protein Structures
— Analysis of conformational changes is one of the keys to the understanding of protein functions and interactions. For the analysis, we often compare two protein structures, tak...
Tetsuo Shibuya
ISMB
2000
14 years 11 months ago
Integrative Analysis of Protein Interaction Data
We have developed a method for the integrative analysis of protein interaction data. It comprises clustering, visualization and data integration components. The method is generall...
Matthias Fellenberg, Kaj Albermann, Alfred Zollner...
JIB
2006
106views more  JIB 2006»
14 years 9 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BMCBI
2010
101views more  BMCBI 2010»
14 years 9 months ago
Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
M. S. Vijayabaskar, Saraswathi Vishveshwara
CORR
2011
Springer
243views Education» more  CORR 2011»
14 years 4 months ago
Localization from Incomplete Noisy Distance Measurements
—We consider the problem of positioning a cloud of points in the Euclidean space Rd , from noisy measurements of a subset of pairwise distances. This task has applications in var...
Adel Javanmard, Andrea Montanari