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JCB
2008
106views more  JCB 2008»
14 years 9 months ago
Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment
Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
James O. Wrabl, Nick V. Grishin
BIRD
2007
Springer
120views Bioinformatics» more  BIRD 2007»
15 years 3 months ago
Joining Softassign and Dynamic Programming for the Contact Map Overlap Problem
Comparison of 3-dimensional protein folds is a core problem in molecular biology. The Contact Map Overlap (CMO) scheme provides one of the most common measures for protein structur...
Brijnesh J. Jain, Michael Lappe
NAR
2000
109views more  NAR 2000»
14 years 9 months ago
The ASTRAL compendium for protein structure and sequence analysis
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included...
Steven E. Brenner, Patrice Koehl, Michael Levitt
BMCBI
2005
158views more  BMCBI 2005»
14 years 9 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
BMCBI
2010
163views more  BMCBI 2010»
14 years 9 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek