126 search results - page 16 / 26 » Protein Structure Comparison and Alignment Using Residue Con... |
75
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BMCBI
2007
14 years 9 months ago
2007
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
BMCBI
2007
14 years 9 months ago
2007
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
BMCBI
2006
14 years 9 months ago
2006
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
CSB
2004
IEEE
15 years 1 months ago
2004
IEEE
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
108
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BMCBI
2004
14 years 9 months ago
2004
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...