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» Protein Structure Prediction: Selecting Salient Features fro...
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BMCBI
2010
127views more  BMCBI 2010»
13 years 6 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
BMCBI
2010
158views more  BMCBI 2010»
13 years 6 months ago
A Bayesian network approach to feature selection in mass spectrometry data
Background: Time-of-flight mass spectrometry (TOF-MS) has the potential to provide non-invasive, high-throughput screening for cancers and other serious diseases via detection of ...
Karl W. Kuschner, Dariya I. Malyarenko, William E....
BMCBI
2010
190views more  BMCBI 2010»
13 years 6 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
JMLR
2011
192views more  JMLR 2011»
13 years 1 months ago
Minimum Description Length Penalization for Group and Multi-Task Sparse Learning
We propose a framework MIC (Multiple Inclusion Criterion) for learning sparse models based on the information theoretic Minimum Description Length (MDL) principle. MIC provides an...
Paramveer S. Dhillon, Dean P. Foster, Lyle H. Unga...
BMCBI
2008
87views more  BMCBI 2008»
13 years 6 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan