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» Protein homology detection with biologically inspired featur...
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BMCBI
2008
93views more  BMCBI 2008»
13 years 6 months ago
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throug
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
Zheng Yin, Xiaobo Zhou, Chris Bakal, Fuhai Li, You...
BMCBI
2008
158views more  BMCBI 2008»
13 years 6 months ago
LC-MSsim - a simulation software for liquid chromatography mass spectrometry data
Background: Mass Spectrometry coupled to Liquid Chromatography (LC-MS) is commonly used to analyze the protein content of biological samples in large scale studies. The data resul...
Ole Schulz-Trieglaff, Nico Pfeifer, Clemens Gr&oum...
BMCBI
2005
124views more  BMCBI 2005»
13 years 6 months ago
Evaluating concentration estimation errors in ELISA microarray experiments
Background: Enzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format perm...
Don Simone Daly, Amanda M. White, Susan M. Varnum,...
BMCBI
2008
126views more  BMCBI 2008»
13 years 6 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...
ROCAI
2004
Springer
13 years 11 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer