Sciweavers

142 search results - page 3 / 29
» Protein sequence and structure alignments within one framewo...
Sort
View
BMCBI
2006
117views more  BMCBI 2006»
13 years 6 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2008
106views more  BMCBI 2008»
13 years 6 months ago
Searching for evolutionary distant RNA homologs within genomic sequences using partition function posterior probabilities
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...
NAR
2008
119views more  NAR 2008»
13 years 6 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
BMCBI
2006
96views more  BMCBI 2006»
13 years 6 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
BMCBI
2005
123views more  BMCBI 2005»
13 years 6 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas