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93
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BMCBI
2010
111views more  BMCBI 2010»
15 years 18 days ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
121
Voted
BMCBI
2010
175views more  BMCBI 2010»
15 years 18 days ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan
113
Voted
BMCBI
2010
149views more  BMCBI 2010»
15 years 18 days ago
KID - an algorithm for fast and efficient text mining used to automatically generate a database containing kinetic information o
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
122
Voted
BMCBI
2008
153views more  BMCBI 2008»
15 years 18 days ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
90
Voted
BMCBI
2010
240views more  BMCBI 2010»
15 years 18 days ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...