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BMCBI
2010
132views more  BMCBI 2010»
14 years 12 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2008
94views more  BMCBI 2008»
14 years 12 months ago
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C...
BMCBI
2008
118views more  BMCBI 2008»
14 years 12 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
CORR
2008
Springer
116views Education» more  CORR 2008»
14 years 12 months ago
An Evidential Path Logic for Multi-Relational Networks
Multi-relational networks are used extensively to structure knowledge. Perhaps the most popular instance, due to the widespread adoption of the Semantic Web, is the Resource Descr...
Marko A. Rodriguez, Joe Geldart
BMCBI
2006
114views more  BMCBI 2006»
14 years 12 months ago
BLISS: biding site level identification of shared signal-modules in DNA regulatory sequences
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
Hailong Meng, Arunava Banerjee, Lei Zhou