276 search results - page 23 / 56 » Quantifying Homology Classes |
121
Voted
BMCBI
2006
15 years 1 months ago
2006
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
132
click to vote
BMCBI
2006
15 years 1 months ago
2006
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
109
Voted
BMCBI
2011
14 years 9 months ago
2011
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
RECOMB
2009
Springer
16 years 2 months ago
2009
Springer
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
120
Voted
BIOCOMP
2008
15 years 3 months ago
2008
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...