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BMCBI
2006
86views more  BMCBI 2006»
14 years 12 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2005
116views more  BMCBI 2005»
14 years 11 months ago
WEBnm@: a web application for normal mode analyses of proteins
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
Siv Midtun Hollup, Gisle Sælensminde, Nathal...
PE
2011
Springer
167views Optimization» more  PE 2011»
14 years 6 months ago
Passage-time computation and aggregation strategies for large semi-Markov processes
High-level semi-Markov modelling paradigms such as semi-Markov stochastic Petri nets and process algebras are used to capture realistic performance models of computer and communic...
Marcel C. Guenther, Nicholas J. Dingle, Jeremy T. ...
BMCBI
2011
14 years 6 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
POLICY
2004
Springer
15 years 5 months ago
A Goal-based Approach to Policy Refinement
As the interest in using policy-based approaches for systems management grows, it is becoming increasingly important to develop methods for performing analysis and refinement of p...
Arosha K. Bandara, Emil Lupu, Jonathan D. Moffett,...