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125
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BMCBI
2007
2007
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
15 years 4 months ago
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
127
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BMCBI
2008
15 years 4 months ago
2008
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
141
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BMCBI
2008
15 years 4 months ago
2008
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
151
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BMCBI
2008
15 years 4 months ago
2008
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
128
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BMCBI
2008
2008
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
15 years 4 months ago
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...