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BMCBI
2008
172views more  BMCBI 2008»
15 years 3 months ago
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
Pelin Armutlu, Muhittin Emre Ozdemir, Fadime Ü...
JCB
2000
137views more  JCB 2000»
15 years 3 months ago
NOTUNG: A Program for Dating Gene Duplications and Optimizing Gene Family Trees
Large scale gene duplication is a major force driving the evolution of genetic functional innovation. Whole genome duplications are widely believed to have played an important rol...
Kevin Chen, Dannie Durand, Martin Farach-Colton
CORR
1999
Springer
124views Education» more  CORR 1999»
15 years 2 months ago
An Algebraic Programming Style for Numerical Software and its Optimization
The abstract mathematical theory of partial differential equations (PDEs) is formulated in terms of manifolds,scalar fields, tensors, and the like, but these algebraic structures a...
T. B. Dinesh, Magne Haveraaen, Jan Heering
126
Voted
RE
2002
Springer
15 years 2 months ago
Extreme Programming Modified: Embrace Requirements Engineering Practices
Extreme Programming (XP) is an agile (lightweight) software development methodology and it becomes more and more popular. XP proposes many interesting practices, but it also has s...
Jerzy R. Nawrocki, Michal Jasiñski, Bartosz...
ESOP
2006
Springer
15 years 7 months ago
Types for Dynamic Reconfiguration
We define a core language combining computational and architectural primitives, and study how static typing may be used to ensure safety properties of component composition and dyn...
João Costa Seco, Luís Caires