- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
We present new, general-purpose kernels for protein structure analysis, and describe how to apply them to structural motif discovery and function classification. Experiments show ...
Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...