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CIBCB
2005
IEEE
14 years 1 days ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
BMCBI
2008
176views more  BMCBI 2008»
13 years 6 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
ICML
2005
IEEE
14 years 7 months ago
New kernels for protein structural motif discovery and function classification
We present new, general-purpose kernels for protein structure analysis, and describe how to apply them to structural motif discovery and function classification. Experiments show ...
Chang Wang, Stephen D. Scott
BMCBI
2008
132views more  BMCBI 2008»
13 years 6 months ago
SCOWLP classification: Structural comparison and analysis of protein binding regions
Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...
BMCBI
2010
118views more  BMCBI 2010»
13 years 6 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...