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BMCBI
2007
139views more  BMCBI 2007»
14 years 9 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
RECOMB
2006
Springer
15 years 9 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
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BMCBI
2007
94views more  BMCBI 2007»
14 years 9 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
ICCS
2009
Springer
15 years 4 months ago
GPU Accelerated RNA Folding Algorithm
Many bioinformatics studies require the analysis of RNA or DNA structures. More specifically, extensive work is done to elaborate efficient algorithms able to predict the 2-D fold...
Guillaume Rizk, Dominique Lavenier
JCB
2008
102views more  JCB 2008»
14 years 9 months ago
Canonical RNA Pseudoknot Structures
In this paper, we study k-noncrossing, -canonical RNA pseudoknot structures with minimum arc-length greater or equal to four. Let T OE4 k; .n/ denote the number of these structure...
Gang Ma, Christian M. Reidys