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BMCBI
2006
153views more  BMCBI 2006»
13 years 6 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2010
161views more  BMCBI 2010»
13 years 3 months ago
Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers
Background: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of ...
Mohammed Dakna, Keith Harris, Alexandros Kalousis,...
BIOINFORMATICS
2010
108views more  BIOINFORMATICS 2010»
13 years 4 months ago
Mass spectrometry data processing using zero-crossing lines in multi-scale of Gaussian derivative wavelet
Motivation: Peaks are the key information in Mass Spectrometry (MS) which has been increasingly used to discover diseases related proteomic patterns. Peak detection is an essentia...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
JMM2
2008
124views more  JMM2 2008»
13 years 6 months ago
Integrated Feature Selection and Clustering for Taxonomic Problems within Fish Species Complexes
As computer and database technologies advance rapidly, biologists all over the world can share biologically meaningful data from images of specimens and use the data to classify th...
Huimin Chen, Henry L. Bart Jr., Shuqing Huang
CSB
2004
IEEE
152views Bioinformatics» more  CSB 2004»
13 years 10 months ago
Comparative Analysis of Gene Sets in the Gene Ontology Space under the Multiple Hypothesis Testing Framework
The Gene Ontology (GO) resource can be used as a powerful tool to uncover the properties shared among, and specific to, a list of genes produced by high-throughput functional geno...
Sheng Zhong, Lu Tian, Cheng Li, Kai-Florian Storch...