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WSC
1998
14 years 11 months ago
ExpertFit: Total Support for Simulation Input Modeling
In this paper, we discuss the critical role of simulation input modeling in a successful simulation study. Two pitfalls in simulation input modeling are then presented and we expl...
Averill M. Law, Michael G. McComas
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2010
123views more  BMCBI 2010»
14 years 9 months ago
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context
Background: Different microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little ov...
Gad Abraham, Adam Kowalczyk, Sherene Loi, Izhak Ha...
BMCBI
2008
144views more  BMCBI 2008»
14 years 9 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...
BMCBI
2006
90views more  BMCBI 2006»
14 years 9 months ago
A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
Background: Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immun...
Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Mural...