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» Rapid detection of significant spatial clusters
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BMCBI
2005
109views more  BMCBI 2005»
14 years 11 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
GISCIENCE
2010
Springer
212views GIS» more  GISCIENCE 2010»
15 years 24 days ago
Qualitative Change to 3-Valued Regions
Regions which evolve over time are a significant aspect of many phenomena in geographic information science. Examples include areas in which a measured value (e.g. temperature, sal...
Matt Duckham, John G. Stell, Maria Vasardani, Mich...
BMCBI
2010
87views more  BMCBI 2010»
14 years 11 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2008
148views more  BMCBI 2008»
14 years 11 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
BMCBI
2010
135views more  BMCBI 2010»
14 years 11 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...