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» Reaction Motifs in Metabolic Networks
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CEC
2009
IEEE
15 years 4 months ago
Gene regulation in a particle metabolome
Abstract— The bacterial genome is well understood by biologists. Although its efficiency and adaptability should make it a good model for evolutionary algorithms, the bacterial ...
Simon J. Hickinbotham, Edward Clark, Susan Stepney...
BMCBI
2010
126views more  BMCBI 2010»
14 years 7 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
BICOB
2009
Springer
15 years 4 months ago
A Bayesian Approach to High-Throughput Biological Model Generation
Abstract. With the availability of hundreds and soon-to-be thousands of complete genomes, the construction of genome-scale metabolic models for these organisms has attracted much a...
Xinghua Shi, Rick L. Stevens
NAR
2007
216views more  NAR 2007»
14 years 9 months ago
SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas
To provide an integrated bioinformatics platform for a systems biology approach to the biology of pseudomonads in infection and biotechnology the database SYSTOMONAS (SYSTems biol...
Claudia Choi, Richard Münch, Stefan Leupold, ...
BMCBI
2008
152views more  BMCBI 2008»
14 years 10 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...