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» Reaction Temperature Constraints in DNA Computing
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GECCO
1999
Springer
13 years 11 months ago
Reaction Temperature Constraints in DNA Computing
Using the thermodynamics of DNA melting, a technique is proposed to choose a reaction temperature for the DNA computation that minimizes the potential for mishybridizations. Adlem...
Russell J. Deaton
CSB
2005
IEEE
166views Bioinformatics» more  CSB 2005»
14 years 28 days ago
Automated Validation of Polymerase Chain Reactions Using Amplicon Melting Curves
PCR, the polymerase chain reaction, is a fundamental tool of molecular biology. Quantitative PCR is the goldstandard methodology for determination of DNA copy numbers, quantitatin...
Tobias P. Mann, Richard Humbert, John A. Stamatoya...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
CrossHybDetector: detection of cross-hybridization events in DNA microarray experiments
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
Paolo Uva, Emanuele de Rinaldis
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
Background: Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allelespecific DNA bands of different lengths by adding four designed primers an...
Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang, Hsu...