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BMCBI
2007
104views more  BMCBI 2007»
14 years 10 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn
CGF
2010
146views more  CGF 2010»
14 years 10 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
DIS
2006
Springer
15 years 1 months ago
Prediction of Domain-Domain Interactions Using Inductive Logic Programming from Multiple Genome Databases
Protein domains are the building blocks of proteins, and their interactions are crucial in forming stable protein-protein interactions (PPI) and take part in many cellular processe...
Thanh Phuong Nguyen, Tu Bao Ho
BMCBI
2006
138views more  BMCBI 2006»
14 years 10 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
KDD
2008
ACM
206views Data Mining» more  KDD 2008»
15 years 10 months ago
Identifying biologically relevant genes via multiple heterogeneous data sources
Selection of genes that are differentially expressed and critical to a particular biological process has been a major challenge in post-array analysis. Recent development in bioin...
Zheng Zhao, Jiangxin Wang, Huan Liu, Jieping Ye, Y...