Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
—This paper presents a study of possible extensions of Pathway Logic to represent and reason about semiquantitative and probabilistic aspects of biological processes. The underly...
Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary f...
Anton Yuryev, Zufar Mulyukov, Ekaterina Kotelnikov...
Background: Cellular processes depend on the function of intracellular molecular networks. The curation of the literature relevant to specific biological pathways is important for...
Ganesh A. Viswanathan, German Nudelman, Sonali Pat...
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...