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BMCBI
2010
126views more  BMCBI 2010»
14 years 7 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
ISCIS
2009
Springer
15 years 4 months ago
A web-based data source for metabolomics
—With the development of improved and cost-effective technologies, it is now possible to detect thousands of metabolites in biofluids or specific organs, and reliably quantify th...
Ali Cakmak, Arun Dsouza, Richard Hanson, Gultekin ...
BMCBI
2007
148views more  BMCBI 2007»
14 years 10 months ago
Toward the automated generation of genome-scale metabolic networks in the SEED
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
BMCBI
2008
155views more  BMCBI 2008»
14 years 10 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
JOBIM
2000
15 years 1 months ago
InterDB, a Prediction-Oriented Protein Interaction Database for C. elegans
Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Nicolas Thierry-Mieg, Laurent Trilling