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BMCBI
2006
216views more  BMCBI 2006»
14 years 10 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
BMCBI
2006
190views more  BMCBI 2006»
14 years 10 months ago
SNPs3D: Candidate gene and SNP selection for association studies
Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
Peng Yue, Eugene Melamud, John Moult
BMCBI
2006
165views more  BMCBI 2006»
14 years 10 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
142views more  BMCBI 2006»
14 years 10 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
CORR
2006
Springer
153views Education» more  CORR 2006»
14 years 9 months ago
Genetic Programming, Validation Sets, and Parsimony Pressure
Fitness functions based on test cases are very common in Genetic Programming (GP). This process can be assimilated to a learning task, with the inference of models from a limited n...
Christian Gagné, Marc Schoenauer, Marc Pari...