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BMCBI
2010
103views more  BMCBI 2010»
15 years 5 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2010
113views more  BMCBI 2010»
15 years 5 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
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BMCBI
2010
189views more  BMCBI 2010»
15 years 5 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
BMCBI
2010
103views more  BMCBI 2010»
15 years 5 months ago
MTRAP: Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of r
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...
Toshihide Hara, Keiko Sato, Masanori Ohya
BMCBI
2010
175views more  BMCBI 2010»
15 years 5 months ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan