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BMCBI
2008
82views more  BMCBI 2008»
15 years 29 days ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BMCBI
2008
143views more  BMCBI 2008»
15 years 29 days ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
130
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 29 days ago
A visual analytics approach for understanding biclustering results from microarray data
Background: Microarray analysis is an important area of bioinformatics. In the last few years, biclustering has become one of the most popular methods for classifying data from mi...
Rodrigo Santamaría, Roberto Therón, ...
BMCBI
2007
163views more  BMCBI 2007»
15 years 29 days ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
119
Voted
BMCBI
2008
140views more  BMCBI 2008»
15 years 29 days ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
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