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84
Voted
BMCBI
2007
14 years 9 months ago
2007
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
BMCBI
2010
14 years 9 months ago
2010
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
91
Voted
BMCBI
2008
14 years 9 months ago
2008
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
BMCBI
2007
14 years 9 months ago
2007
Background: Over the past decade, a number of tools have emerged for the examination of homology relationships among protein sequences in a structural context. Most recent softwar...
65
Voted
BMCBI
2010
14 years 9 months ago
2010
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...