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100
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BMCBI
2010
15 years 26 days ago
2010
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
108
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BMCBI
2010
15 years 26 days ago
2010
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
96
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BMCBI
2007
15 years 26 days ago
2007
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
90
Voted
BMCBI
2007
15 years 26 days ago
2007
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
110
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BMCBI
2007
15 years 26 days ago
2007
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...