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» Recognizing Gene and Protein Function in MEDLINE Abstracts
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BMCBI
2010
131views more  BMCBI 2010»
14 years 7 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom
HYBRID
2001
Springer
15 years 2 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
BMCBI
2007
142views more  BMCBI 2007»
14 years 10 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
MCS
2009
Springer
15 years 4 months ago
True Path Rule Hierarchical Ensembles
Abstract. Hierarchical classification problems gained increasing attention within the machine learning community, and several methods for hierarchically structured taxonomies have...
Giorgio Valentini
BIBE
2005
IEEE
121views Bioinformatics» more  BIBE 2005»
15 years 3 months ago
RNA Pseudoknot Prediction Using Term Rewriting
RNA plays a critical role in mediating every step of cellular information transfer from genes to functional proteins. Pseudoknots are widely occurring structural motifs found in a...
Xuezheng Fu, Hao Wang, William L. Harrison, Robert...